RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
miR-130a-3p
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
TGF-BRI; TGF-BRII
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2
Year
2017
Function
Mir-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting tgfbr1 and tgfbr2.